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DNA not solely responsible for inheritance

slo1
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4/6/2015 8:50:00 AM
Posted: 1 year ago
http://www.sciencedaily.com...

Characteristics passed between generations are not decided solely by DNA, but can be brought about by other material in cells, new research shows.

Scientists studied proteins found in cells, known as histones, which are not part of the genetic code, but act as spools around which DNA is wound. Histones are known to control whether or not genes are switched on.

Researchers found that naturally occurring changes to these proteins, which affect how they control genes, can be sustained from one generation to the next and so influence which traits are passed on.

The finding demonstrates for the first time that DNA is not solely responsible for how characteristics are inherited. It paves the way for research into how and when this method of inheritance occurs in nature, and if it is linked to particular traits or health conditions.

It may also inform research into whether changes to the histone proteins that are caused by environmental conditions -- such as stress or diet -- can influence the function of genes passed on to offspring.

The research confirms a long-held expectation among scientists that genes could be controlled across generations by such changes. However, it remains to be seen how common the process is, researchers say.

Scientists tested the theory by carrying out experiments in a yeast with similar gene control mechanisms to human cells. They introduced changes to a histone protein, mimicking those that occur naturally, causing it to switch off nearby genes. The effect was inherited by subsequent generations of yeast cells.

The study, published in Science, was supported by the Wellcome Trust and the EC EpiGeneSys Network.

Professor Robin Allshire, of the University of Edinburgh's School of Biological Sciences, who led the study, said: "We've shown without doubt that changes in the histone spools that make up chromosomes can be copied and passed through generations. Our finding settles the idea that inherited traits can be epigenetic, meaning that they are not solely down to changes in a gene's DNA."
slo1
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4/6/2015 8:56:55 AM
Posted: 1 year ago
Just more proof of environmental passing of traits. A while back I posted a finding that found parents in starvation type environments seemed to pass some type of inheritance for generations. I believe the study in worms found that up to 3 generations of worms lived longer due to the changes the body goes through when in starvation mode even though those generations never had a lack of food.

When one adds in genetics as a variable in evolutionary models it probably helps support how a split population of organisms could evolve differently. Just another tool int he tool box other than mutations, which many find distasteful due to the appearance of randomness.