It is well known that playing a musical instrument encourages creativity. It is not well known, however, that studies indicate that certain musical instruments have the ability to alter brain waves. Percussion instruments, in particular, have the ability to actually affect brain activity. In this respect playing a musical instrument both literally and figuratively affects brain activity.
Playing a musical instrument could probably affect your brain. Music has been known to help people learn better and remember phrases easier, not to mention classical music has been said to increase young childrens knowledge. It is all how you use it and look at it. But yes, I do think it can affect it.