Alcohol in moderation does not suppress the will to change our lives for the better. Consistently drinking alcohol does. Alcohol can be a good thing. Family reunions, parties with close friends, and many other occasions create long-lasting and positive memories with alcohol involved. The few bad should not weigh down the large amount of good.
I do believe that alcohol affects Americans horribly these days. it doesn't seem to ever bring out the good in anyone. Instead, it brings out everyone's inner ugly. People say and do sinful and hateful things under the influence of alcohol. Alcohol consumption breeds unholy physical relations, infidelity, domestic violence and more. Aside from that, people get into devastating auto accidents. This is very, very bad, especially since alcohol is so readily available and legal.
Alcoholism affects millions of Americans every day. It contributes to depression and suicide. Drinking irresponsibly causes thousands of unnecessary deaths each year across the country. To say that alcohol does not affect Americans is simply not true. This legal drug kills more Americans each year than illegal drugs combined but that fact is rarely ever mentioned.
I don't believe it should be illegal, but there are many Americans who struggle with alcoholism. It affects their ability to work and family relationships. For people who are truly addicted, Nietzsche's position is correct. Given that about 3/4 of all adults in the US consume alcohol and 6% or so of those are alcoholics, it definitely has an impact.