Yes, I believe there is a very thin line between intelligence and insanity.
No, I believe that intelligence and insanity far from each other or are polar opposites.
Exhibit A: Owlz.
The gene called nueregulin 1 plays a role in brain development but a variant of it is associated with mental illness like schizophrenia and bi polar. This same creative gene has been found in geniuses like Van Gogh and Sylvia Plath and is linked to psychosis and depression. People with this gene are usually very high achievers, but usually suffer from some sort of depression or other disorder. -----Journal of Psychological Science